Filippo Crea
For the podcast associated with this article, please visit https://academic-oup-com.libproxy.ucl.ac.uk/eurheartj/pages/Podcasts . This Focus Issue on cardio-oncology, heart failure and cardiomyopathies, and digital health and innovation contains the review ‘Use of new and emerging cancer drugs: what the cardiologist needs to know’ by ...
Latest articles
Research Article
Therapy duration and improvement of ventricular function in de novo heart failure: the Heart Failure Optimization studyChristian Veltmann and others
European Heart Journal, ehae334, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae334
Background and Aims In patients with de novo heart failure with reduced ejection fraction (HFrEF), improvement of left ventricular ejection fraction (LVEF) is expected to occur when started on guideline-recommended medical therapy. However, improvement may not be completed within 90 days. Methods Patients with HFrEF and ...
Editorial
Brugada syndrome: can polygenic risk scores help the clinician?Elijah R Behr
European Heart Journal, ehae364, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae364
This editorial refers to ‘Brugada syndrome in Japan and Europe: a genome-wide association study reveals shared genetic architecture and new risk loci’, by T. Ishikawa et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae251 . Brugada syndrome (BrS) is a heritable disorder predisposing to sudden cardiac arrest (SCA) and sudden ...
Editorial
Accelerated high sensitivity troponin diagnostics: ready for an even faster pace?Evangelos Giannitsis and others
European Heart Journal, ehae344, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae344
This editorial refers to ‘Point–of–care high–sensitivity cardiac troponin in suspected acute myocardial infarction assessed at baseline and 2 h by L. Cullen et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae343 . High sensitivity cardiac troponin (hs-cTn) assays were introduced into clinical routine almost 15 years ago. 1 ...
Editorial
Challenge–skill balance in cardiac surgery: an attempt to explain sex-related differences in coronary surgeryTorsten Doenst and Gloria Faerber
European Heart Journal, ehae350, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae350
This editorial refers to ‘Multiple arterial versus single arterial coronary artery bypass grafting: sex-related differences in outcomes’, by J. Ren et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae294 . It is currently debated whether women receive inferior care compared with men in the cardiovascular arena. Coronary ...
Research Article
Evinacumab in hom*ozygous familial hypercholesterolaemia: long-term safety and efficacyDaniel Gaudet and others
European Heart Journal, ehae325, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae325
Background and Aims hom*ozygous familial hypercholesterolaemia (HoFH) is a rare genetic disorder characterized by severely elevated LDL cholesterol (LDL-C) and premature atherosclerotic cardiovascular disease. In the pivotal Phase 3 HoFH trial (NCT03399786), evinacumab significantly decreased LDL-C in patients with HoFH. ...
Editorial
ANGPTL3 as a therapeutic target for treating hom*ozygous familial hypercholesterolaemia: a shot in the arm for evinacumabGerald F Watts and others
European Heart Journal, ehae321, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae321
This editorial refers to ‘Long-term safety and effiacy of evinacumab in patients with hom*ozygous familial hypercholesterolaemia’, by D. Gaudet et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae325 . hom*ozygous familial hypercholesterolaemia (HoFH) is an ultra rare, co-dominantly inherited condition characterized by marked ...
Research Article
Loop diuretic utilisation with or without heart failure: impact on prognosisJocelyn M Friday and others
European Heart Journal, ehae345, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae345
Background & Aims Many patients are prescribed loop diuretics without a diagnostic record of heart failure. Little is known about their characteristics and prognosis. Methods Glasgow regional health records (2009-2016) were obtained for adults with cardiovascular disease or taking loop diuretics. Outcomes were ...
Research Article
Office measurement vs. ambulatory blood pressure monitoring: associations with mortality in patients with or without diabetesMichael Böhm and others
European Heart Journal, ehae337, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae337
Background and Aims Guidelines suggest similar blood pressure (BP) targets in patients with and without diabetes and recommend ambulatory BP monitoring (ABPM) to diagnose and classify hypertension. It was explored whether different levels of ambulatory and office BP and different hypertension phenotypes associate with ...
Editorial
Risk prediction by ambulatory blood pressure monitoring in non-diabetic and diabetic patients: better than office measurementsGiuseppe Mancia and others
European Heart Journal, ehae171, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae171
This editorial refers to ‘Office measurement vs. ambulatory blood pressure monitoring: associations with mortality in patients with or without diabetes’, by M. Böhm et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae337 . This issue of the European Heart Journal includes a study by Bohm and colleagues 1 based on a large ...
Research Article
Polygenic risk score adds to a clinical risk score in the prediction of cardiovascular disease in a clinical settingNilesh J Samani and others
European Heart Journal, ehae342, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae342
Background and Aims A cardiovascular disease polygenic risk score (CVD-PRS) can stratify individuals into different categories of cardiovascular risk, but whether the addition of a CVD-PRS to clinical risk scores improves the identification of individuals at increased risk in a real-world clinical setting is unknown. ...
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Editor-in-ChiefProfessor Filippo Crea
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Guidelines
2023 ESC Guidelines for the management of cardiomyopathies
ByElena Arbelo and others
Published: 25 August 2023
2023 ESC Guidelines for the management of endocarditis
ByVictoria Delgado and others
Published: 25 August 2023
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes
By Nikolaus Marx and others
Published: 25 August 2023
2023 ESC Guidelines for the management of acute coronary syndromes
By Robert A Byrne and others
Published: 25 August 2023
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